Angel Sosa is 4 years old and has not exactly had an easy ride in life. Born to loving parents and a large family he entered this world saddled with lots of neurological and physical challenges. Among them: Infantile spasms, a difficult-to-treat form of childhood-onset epilepsy called Lennox–Gastaut syndrome (LGS) or simply Lennox syndrome, and developmental delays. According to his loving Mum, Monique, he was ““having 10 clusters of 10-11 seizures lasting six (6) minutes each day and was having ten tonic seizures a day sometimes lasting up to 3 minutes without breathing.”
As you might expect little Angel’s early life was spent seeing doctors and therapists and taking drugs to control his epilepsy (Three currently: Felbamate, Valproic acid, and Zonisemide). Naturally, his parents kept an eye on the news and the Web for any medical advances that might offer any hope of remediating their son’s intractable epilepsy and other challenges. With the advent and growth of adult (nonembryonic) stem cell treatment programs outside the US they saw evidence that perhaps some form of stem cell therapy could help their little boy. As they sorted through the various private stem cell medicine operations abroad they came across accounts of the many turnarounds in children effected by Nova Cell’s primed stem cell treatments and intravenous use of its proprietary Beacon Factor. This encouraged Monique to reach out to NCIM patient educator & care facilitator, Grace (Ph.D. candidate), by phone. Grace then walked her through what NCIM doctors and scientists had accomplished and documented in treated patients and then ably tackled all her questions and concerns. Satisfied with what she had learned, the Sosa’s, enrolled their son in the NCIM treatment program and read the patient handbook (This link is to the abridged version of NCIM’s patient handbook. Those who wish to access the full version must register). Later, on the heels of Angel’s approval for treatment by NCIM physicians including a pediatric neurologist, she and her husband booked him for care on 6 February (2014).
When the “big day” arrived for Angel, Grace noted this about the little boy:
While waiting for his treatment Angel was very stiff and somewhat arching backward. His eyes were moving around the room randomly and, though he would look at you if you called his name after a couple of times, he did so only for a split second and it seemed that he saw right through you. His mom had to give him his dose of medications because he was getting a little more stiff and she knew they were wearing off.
Angel SosaAngel was then given primed umbilical cord stem cells and the Beacon Factor. Grace noted this at the time:
About an hour after his stem cell treatment Angel’s mom mentioned to us that both she and his father were impressed with how relaxed Angel is including his normally stiff legs. As the attending physician was checking him in recovery Angel did something amazing: He fixed his gaze on him for about 5 seconds. The doctor was both amazed and incredulous. Then Angel’s father said ‘Oh yea, he already has focused his gaze on his mom and I.’ Within an hour Angel was already aware of his surroundings and the people around him.
In addition, Angel’s legs which were normally ice cold were now pink and warm and remained so.
After Angel got home and settled in Monique shared this with Grace by phone and later by email:
The Thursday morning of his stem cell treatment he had 3 tonic seizures and then after stem cells no more seizures till late Sunday night he had 2 small quick seizures. All this week he’s only had 3 seizures! And no big seizures at all! No more 6 minute clusters🙂
In therapy his therapists have noticed improvements already! He feels so much stronger! He is tolerating standing a little more and one of his therapists noticed he was using the muscles on his arm and shoulders. Everyone has noticed that he’s more alert and happy and has more energy! On Tuesday he looked at me and smiled Mind you, he has never smiled for no reason.
Monique added that Angel’s three (3) year old sister was super excited by the fact her brother was following her all over the place with his eyes, something she instinctively regarded as a form of playing with her.
She concluded with this:
Thank you NOVA!!! I’m so excited about seeing more gains with my angel! Thank you Grace and Abel!
The Sosa’s have set up a Facebook page for Angel which is at https://www.facebook.com/angel.sosa.52?fref=ts. This page contains photos, videos, posts and more.
CHECK OUT THIS EXCITING UPDATE POSTED ON ANGEL SOSA’S FACEBOOK PAGE:
Since having done stem cells February 6, angel went 24 days without a Tonic seizure!! Before stem cells he was having them everyday 2-4 a day. It only lasted a couple seconds and recovered great afterwards. And with the cluster of infantile spasms some days it seems like there’s none and other days he will have 1-2 maybe lasting only a couple seconds and before he was having 2-4 clusters a day lasting 6-10 mins everyday!! I have also completely weaned him off zonegran his last dose was February 28. So now he’s only on 2 meds depakote and felbamate.
Hardly any other illness can be traced back in medical history as far as epilepsy can. Many pointers from early history indicate that this condition has been part of the human lot from the very beginning. Then as now, it is one of the most common chronic diseases that there are: 0.5% of all human beings suffer from epilepsy.
The causes of Epilepsy
How can epilepsy be defined? When someone repeatedly has epileptic seizures then we say that that person is suffering from epilepsy. An epileptic seizure itself is one of the many pathological forms of reaction which can take place in the brain; it is the brain’s "response" or reaction to a disturbing, irritating or damaging stimulus. This reaction to the stimulus is accompanied by abnormal electro-chemical excitatory processes in the cerebral nerve cells. This pathological process takes place when suddenly an unnaturally large number of nerve cells are stimulated simultaneously, causing a difference in voltage between the outer side of the cell wall and the inside of the cell (membrane potential). This voltage difference is then suddenly discharged, creating a kind of "storm in the brain", or, to put it another way, "making a fuse blow".
If a person has one epileptic fit, it does not mean that he or she has epilepsy. Only when that person suffers repeated spontaneous epileptic seizures (i.e. without any direct trigger), should they be diagnosed as having epilepsy. Epilepsy is therefore always a chronic illness which can go on for many years (but which does not necessarily last a lifetime!).
The term "epilepsy" is derived from the Greek word "epilambanein", which means "to seize upon", "to attack". Thus epilepsy is a seizure or rather a disease which causes seizures to occur. As, however, there are many very different types of seizure, it is better to speak of epilepsies.
Epileptic seizures can look very different. There is hardly any function of the brain which cannot also be part of an epileptic seizure. As a result, seizures can manifest themselves in many different ways: in movements (e.g. jerking, trembling, stiffening of the muscles), in paralgiae/ sensory disturbances (e.g. tingling, numbness, hearing or seeing something), in so-called vegetative signs (e.g. flushing, lips turning blue, salivation, bowel sounds, wetting oneself), or in psychological changes (e.g. fear, sudden memory impairment, loss of consciousness).